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Editorial Board oversight: Borislav Alexiev, M.D. (last reviewed January 2023), Jose G. Mantilla, M.D. (last reviewed November 2023), Nasir Ud Din, M.B.B.S. (last reviewed January 2023), Farres Obeidin, M.D. (last reviewed November 2023)
Table of contents
General:books grading histology-blood vessels histology-brown and white adipose histology-fibrous tissue & nerve histology-skeletal muscle histology-smooth muscle ISSVA classification for vascular anomalies (pending) soft tissue and bone molecular staging staging-GIST syndromes WHO classification WHO classification-GI mesenchymal tumors WHO reporting system for soft tissue cytopathology (pending)
Adipose tissue tumors
Lipoma and variants:lipoma angiolipoma chondroid lipoma myolipoma spindle cell / pleomorphic lipoma
Other benign lesions:hibernoma lipoblastoma / lipoblastomatosis lipomatosis lipomatosis of nerve
Liposarcoma:atypical lipomatous tumor / well differentiated liposarcoma atypical spindle cell / pleomorphic lipomatous tumor dedifferentiated liposarcoma myxoid liposarcoma myxoid pleomorphic liposarcoma pleomorphic liposarcoma
Extraskeletal bone tumors:extraskeletal osteosarcoma soft tissue chondroma
Fibroblastic / myofibroblastic:angiofibroma of soft tissue angiomyofibroblastoma calcifying aponeurotic fibroma calcifying fibrous tumor cellular angiofibroma dermatofibrosarcoma protuberans (DFSP) desmoplastic fibroblastoma elastofibroma EWSR1::SMAD3 positive fibroblastic tumor fibroma of tendon sheath fibrous hamartoma of infancy focal myositis Gardner fibroma giant cell fibroblastoma inflammatory myofibroblastic tumor intranodal palisaded myofibroblastoma ischemic fasciitis myositis ossificans and fibro-osseous pseudotumor of digits nodular fasciitis nuchal type fibroma proliferative fasciitis proliferative myositis solitary fibrous tumor superficial acral fibromyxoma superficial CD34+ fibroblastic tumor
Fibromatosis:fibromatosis-desmoid fibromatosis-palmar / plantar fibromatosis colli inclusion body fibromatosis juvenile hyaline fibromatosis lipofibromatosis
Fibrosarcoma:adult fibrosarcoma infantile fibrosarcoma low grade fibromyxoid sarcoma low grade myofibroblastic sarcoma myxofibrosarcoma myxoinflammatory fibroblastic sarcoma sclerosing epithelioid fibrosarcoma
So called fibrohistiocytic:fibrohistiocytic tumors-general deep fibrous histiocytoma giant cell tumor of soft tissue plexiform fibrohistiocytic tumor tenosynovial giant cell tumor
Gastrointestinal stromal tumor:gastrointestinal stromal tumor (GIST)
Peripheral nerve
Neurofibroma:neurofibroma-general plexiform neurofibroma
Other benign:benign triton tumor / neuromuscular choristoma dermal nerve sheath myxoma ectopic meningioma (pending) granular cell tumor hybrid nerve sheath tumor (pending) neuroma perineurioma schwannoma solitary circumscribed neuroma
Malignant:malignant melanotic nerve sheath tumor malignant peripheral nerve sheath tumor (MPNST)
Skeletal muscle:ectomesenchymoma rhabdomyoma
Rhabdomyosarcoma:alveolar rhabdomyosarcoma embryonal rhabdomyosarcoma pleomorphic rhabdomyosarcoma spindle cell / sclerosing rhabdomyosarcoma
Smooth muscle:Epstein-Barr virus associated smooth muscle tumor leiomyoma
Leiomyosarcoma:leiomyosarcoma-general inflammatory leiomyosarcoma
Vascular
Nonneoplastic:arteriovenous malformation verrucous venous malformation (pending) papillary endothelial hyperplasia atypical vascular lesion post radiation
Benign:anastomosing hemangioma cystic / cavernous lymphangioma epithelioid hemangioma hemangioma & variants intramuscular angioma lymphangioendothelioma lymphangioma venous hemangioma
Intermediate (locally aggressive / rarely metastasizing):composite hemangioendothelioma epithelioid hemangioendothelioma kaposiform hemangioendothelioma & tufted angioma Kaposi sarcoma papillary intralymphatic angioendothelioma pseudomyogenic hemangioendothelioma retiform hemangioendothelioma
Malignant:angiosarcoma
Pericytic (perivascular):angioleiomyoma glomus tumor myopericytoma / myofibroma
Uncertain differentiation:alveolar soft part sarcoma angiomatoid fibrous histiocytoma CIC rearranged sarcoma clear cell sarcoma desmoplastic small round cell tumor epithelioid sarcoma Ewing sarcoma extrarenal rhabdoid tumor extraskeletal myxoid chondrosarcoma intimal sarcoma intramuscular myxoma juxta-articular myxoma keratin positive giant cell tumor / xanthogranulomatous epithelial tumor myoepithelioma / myoepithelial carcinoma / mixed tumor myospherulosis NTRK rearranged spindle cell neoplasm (pending) ossifying fibromyxoid tumor perivascular epithelioid cell tumor (PEComa) phosphaturic mesenchymal tumor pleomorphic hyalinizing angiectatic tumor PRRX1 rearranged mesenchymal tumors (pending) synovial sarcoma undifferentiated / unclassified sarcoma
Other nonneoplastic:hematoma Morel-Lavallée lesions (pending) Morton neuroma mycobacterial spindle cell tumor necrotizing fasciitis tumoral calcinosis
Soft tissue stains: AE1 / AE3 ALK1 caldesmon CAMTA1 CCNB3 (pending) CD31 CD34 CD99 CDK4 D2-40 DDIT3 (pending) desmin DOG1 DUX4 EBER EMA ERG factor XIIIa FLI1 FOSB (pending) GLUT1 H3K27me3 HHV8 / LANA1 HMB45 c-kit / CD117 MDM2 MelanA MUC4 MYOD1 myogenin NKX2.2 (pending) NR4A3 (pending) pan-TRK PROX1 (pending) RB1 S100 SDHB SMARCA4 / BRG1 SMARCB1 / IN1 SMA SOX10 STAT6 SYT / SSX (pending) TFE3 TLE1 WT1

Superpages: entire chapterimagesvirtual slides
Index (Alphabetical table of contents)
A-E:adult fibrosarcoma alveolar rhabdomyosarcoma alveolar soft part sarcoma anastomosing hemangioma angiofibroma of soft tissue angioleiomyoma angiolipoma angiomatoid fibrous histiocytoma angiomyofibroblastoma angiosarcoma arteriovenous malformation atypical lipomatous tumor / well differentiated liposarcoma atypical spindle cell / pleomorphic lipomatous tumor atypical vascular lesion post radiation benign triton tumor / neuromuscular choristoma calcifying aponeurotic fibroma calcifying fibrous tumor cellular angiofibroma chondroid lipoma CIC rearranged sarcoma clear cell sarcoma composite hemangioendothelioma cystic / cavernous lymphangioma dedifferentiated liposarcoma deep fibrous histiocytoma dermal nerve sheath myxoma dermatofibrosarcoma protuberans (DFSP) desmoplastic fibroblastoma desmoplastic small round cell tumor ectomesenchymoma ectopic meningioma (pending) elastofibroma embryonal rhabdomyosarcoma epithelioid hemangioendothelioma epithelioid hemangioma epithelioid sarcoma Epstein-Barr virus associated smooth muscle tumor Ewing sarcoma EWSR1::SMAD3 positive fibroblastic tumor extrarenal rhabdoid tumor extraskeletal myxoid chondrosarcoma extraskeletal osteosarcoma
F-N:fibrohistiocytic tumors-general fibroma of tendon sheath fibromatosis colli fibromatosis-desmoid fibromatosis-palmar / plantar fibrous hamartoma of infancy focal myositis Gardner fibroma gastrointestinal stromal tumor (GIST) giant cell fibroblastoma giant cell tumor of soft tissue glomus tumor grading granular cell tumor hemangioma & variants hematoma hibernoma histology-blood vessels histology-brown and white adipose histology-fibrous tissue & nerve histology-skeletal muscle histology-smooth muscle hybrid nerve sheath tumor (pending) inclusion body fibromatosis infantile fibrosarcoma inflammatory leiomyosarcoma inflammatory myofibroblastic tumor intimal sarcoma intramuscular angioma intramuscular myxoma intranodal palisaded myofibroblastoma ischemic fasciitis ISSVA classification for vascular anomalies (pending) juvenile hyaline fibromatosis juxta-articular myxoma Kaposi sarcoma kaposiform hemangioendothelioma & tufted angioma keratin positive giant cell tumor / xanthogranulomatous epithelial tumor leiomyoma leiomyosarcoma-general lipoblastoma / lipoblastomatosis lipofibromatosis lipoma lipomatosis lipomatosis of nerve low grade fibromyxoid sarcoma low grade myofibroblastic sarcoma lymphangioendothelioma lymphangioma malignant melanotic nerve sheath tumor malignant peripheral nerve sheath tumor (MPNST) Morel-Lavallée lesions (pending) Morton neuroma mycobacterial spindle cell tumor myoepithelioma / myoepithelial carcinoma / mixed tumor myolipoma myopericytoma / myofibroma myositis ossificans and fibro-osseous pseudotumor of digits myospherulosis myxofibrosarcoma myxoid liposarcoma myxoid pleomorphic liposarcoma myxoinflammatory fibroblastic sarcoma necrotizing fasciitis neurofibroma-general neuroma nodular fasciitis NTRK rearranged spindle cell neoplasm (pending) nuchal type fibroma
O-Z:ossifying fibromyxoid tumor papillary endothelial hyperplasia papillary intralymphatic angioendothelioma perineurioma perivascular epithelioid cell tumor (PEComa) phosphaturic mesenchymal tumor pleomorphic hyalinizing angiectatic tumor pleomorphic liposarcoma pleomorphic rhabdomyosarcoma plexiform fibrohistiocytic tumor plexiform neurofibroma proliferative fasciitis proliferative myositis PRRX1 rearranged mesenchymal tumors (pending) pseudomyogenic hemangioendothelioma retiform hemangioendothelioma rhabdomyoma schwannoma sclerosing epithelioid fibrosarcoma soft tissue and bone molecular soft tissue chondroma solitary circumscribed neuroma solitary fibrous tumor spindle cell / pleomorphic lipoma spindle cell / sclerosing rhabdomyosarcoma staging staging-GIST superficial acral fibromyxoma superficial CD34+ fibroblastic tumor syndromes synovial sarcoma tenosynovial giant cell tumor tumoral calcinosis undifferentiated / unclassified sarcoma venous hemangioma verrucous venous malformation (pending) WHO classification WHO classification-GI mesenchymal tumors WHO reporting system for soft tissue cytopathology (pending)
Soft tissue books

Bocklage: 2014

Boto: 2016

Dodd: 2014

Fisher: 2015

Folpe: 2022

Goldblum: 2019

Hornick: 2018

Horvai: 2012

IARC: 2020

Jiang: 2023

Lindberg: 2019

Miettinen: 2016

Mody: 2022

Montgomery: 2018

Montgomery: 2020

Paolo Dei Tos : 2019

Perry: 2017



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