Breast - nonmalignant
Inflammatory / infectious
Sarcoidosis

Author: Hind Nassar, M.D. (see Authors page)

Revised: 27 July 2017, last major update April 2010

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Sarcoidosis [title] breast

Cite this page: Sarcoidosis. PathologyOutlines.com website. http://pathologyoutlines.com/topic/breastsarcoidosis.html. Accessed August 24th, 2017.
Definition / general
  • Idiopathic systemic granulomatous disorder of noncaseating, epithelioid granulomas with multinucleated giant cells
  • Usually involves lungs with fibrosis; also lymph nodes, skin, liver, spleen, phalanges, bones, parotid gland
  • Rare in breast; either begins in breast or part of known disease
Clinical features
Radiology images

Images hosted on PathOut server:

Mammogram, courtesy of Dr. Mark R. Wick

Case reports
Clinical images

Images hosted on PathOut server:

Breast skin, courtesy of Dr. Mark R. Wick

Microscopic (histologic) description
  • Noncaseating, epithelioid granulomas with multinucleated giant cells
  • No / rare necrosis
Microscopic (histologic) images

Images hosted on PathOut server:

Courtesy of Dr. Mark R. Wick

Parenchyma, courtesy of Dr. Mark R. Wick

Breast skin, courtesy of Dr. Mark R. Wick

Stromal granulomas sparing lobules

DCIS (arrow) with sarcoid-like granuloma

Infiltrating lobular
carcinoma and
sarcoid-like
granuloma



Images hosted on other servers:

Nonnecrotizing granulomatous inflammation

Lymph node

Cytology description
  • Epithelioid cells and lymphocytes
Differential diagnosis