Thyroid & parathyroid

Thyroid cancer

Children



Last author update: 1 March 2009
Last staff update: 27 January 2021

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PubMed Search: pediatric thyroid cancer

Shahid Islam, M.D., Ph.D.
Cite this page: Islam S. Children. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/thyroidthyroidcarcinomachildren.html. Accessed December 20th, 2024.
Definition / general
  • Papillary (80%), follicular (10 - 20%), some cases historically may have been follicular variant of papillary carcinoma or Hürthle cell neoplasms (Am J Clin Pathol 2000;114:681), medullary (5%), anaplastic (rare)
Epidemiology
Clinical features
  • Regional nodal metastases occur in 60 - 80%, distant metastases in 10 - 20% at diagnosis, often lung
Prognostic factors
Case reports
Molecular / cytogenetics description
  • RET rearrangements more common than adults, BRAF activation less common (20% versus 77% in adults, Mod Pathol 2005;18:898)
Videos

Pediatric thyroid nodules by A. Wassner and A. Bauer (2020)

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