Thyroid & parathyroid
Other thyroid nonneoplastic
Postoperative spindle cell nodule
Author: Sheren Younes, M.D., Ph.D.
Last author update: 1 August 2014
Last staff update: 31 December 2020
Copyright: 2014-2024, PathologyOutlines.com, Inc.
PubMed Search: postoperative spindle cell thyroid
Table of Contents
Definition / general | Clinical features | Radiology description | Case reports | Microscopic (histologic) description | Microscopic (histologic) images | Cytology description | Cytology images | Positive stains | Electron microscopy description | Differential diagnosisCite this page: Younes S. Postoperative spindle cell nodule. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/thyroidpostop.html. Accessed December 4th, 2024.
Definition / general
- Occurs after FNA or surgery
- Rare, reported in other sites as genitourinary system and breast (Am J Clin Pathol 1999;111:70)
Clinical features
- Thyroid mass
- History of surgery or FNA
Radiology description
- Hypoechoic mass with calcification (Korean J Pathol 2013;47:89)
Case reports
- 31 year old woman with postoperative spindle cell nodule after thyroidectomy (Head Neck 2013;35:E13)
- 53 year old woman with postoperative spindle cell nodule in neck after thyroidectomy (Korean J Pathol 2013;47:89)
Microscopic (histologic) description
- Spindle cell proliferation
- Bland cytology, no pleomorphism
- Low mitotic count, no atypical mitoses
- Other features may be seen as scattered inflammatory cells and histiocytes, focal myxoid change and delicate blood vessels
Microscopic (histologic) images
Images hosted on other servers:
Gross and microscopic findings
Cytology description
- Spindle cells with histiocytes, vague granulomatous pattern
Cytology images
Images hosted on other servers:
Fragments of fibrocollagenous tissue
Electron microscopy description
- Characteristic myofibroblastic features
Differential diagnosis
- Recurrence of the lesion
- Spindle cell lesions of the thyroid:
- Medullary carcinoma
- Sarcoma
- Schwannoma
