Thyroid & parathyroid

Thyroiditis

Palpation thyroiditis



Last author update: 1 March 2009
Last staff update: 31 August 2023

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PubMed search: palpation thyroiditis

Shahid Islam, M.D., Ph.D.
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Cite this page: Islam S. Palpation thyroiditis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/thyroidpalpation.html. Accessed November 27th, 2024.
Definition / general
  • Common (85%+ of surgically resected thyroids) but clinically insignificant
Terminology
  • Also called multifocal granulomatous thyroiditis
Clinical features
Case reports
Treatment
  • Self limited, no treatment necessary
Gross description
  • Normal, or small foci of hemorrhage
Microscopic (histologic) description
  • Multiple small granulomas centered in disrupted follicles, composed of lymphocytes (usually T cells), macrophages (some foamy), occasional multinucleated giant cells associated with colloid breakdown, usually no necrosis, no neutrophils
Microscopic (histologic) images

Contributed by Andrey Bychkov, M.D., Ph.D. and AFIP

Superficially
located nodule

Intrafollicular
granulomatous
reaction

Granulomatous folliculitis

Multinucleated giant cells

Histiocytes within follicle

Histiocytes are strongly lysozyme+



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Granuloma

Differential diagnosis
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