Thyroid & parathyroid
Other uncommon thyroid carcinomas
Mixed medullary-follicular tumors
Author: Shahid Islam, M.D., Ph.D.
Last author update: 1 March 2009
Last staff update: 24 September 2020
Copyright: 2003-2024, PathologyOutlines.com, Inc.
PubMed Search: mixed medullary-follicular tumor
Related Topic: Medullary carcinoma
Table of Contents
Definition / general | Case reports | Microscopic (histologic) images | Positive stains | Differential diagnosisCite this page: Islam S. Mixed medullary-follicular tumors. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/thyroidmedullarymixed.html. Accessed December 20th, 2024.
Definition / general
- Aggressive
Case reports
- 44 year old man with lymph node metastases (Mod Pathol 1996;9:631)
- 51 year old woman with medullary and follicular carcinoma in the same thyroid lobe (Hum Pathol 1989;20:83)
Microscopic (histologic) images
AFIP images
Tumor cells show lobular growth pattern
Scattered early follicle-like areas
Tumor cells form colloid containing follicles
Many cells have clear cytoplasm
Immunofluorescent staining
Positive stains
Differential diagnosis
- Entrapping of thyroid follicles by medullary carcinoma
- Medullary carcinoma with glandular growth pattern
