Stomach
Infectious
Helicobacter heilmannii
Author: Elliot Weisenberg, M.D.
Last author update: 1 August 2012
Last staff update: 7 June 2024
Copyright: 2003-2024, PathologyOutlines.com, Inc.
PubMed Search: Helicobacter heilmannii gastritis
Table of Contents
Definition / general | Treatment | Microscopic (histologic) description | Microscopic (histologic) images | Positive stains | Additional references | Board review style question #1 | Board review style answer #1Cite this page: Weisenberg E. Helicobacter heilmannii. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stomachhh.html. Accessed December 22nd, 2024.
Definition / general
- Very rare compared to H. pylori (Arch Pathol Lab Med 1995;119:1149)
- Patients usually symptomatic with dyspepsia, epigastric pain, acid reflux
- Associated with lymphoid hyperplasia, lymphoma, gastric carcinoma, peptic ulcer disease
- Less severe and fewer lymphoid aggregates than H. pylori gastritis (Mod Pathol 1999;12:534)
- More common in children; due to contact with farm animals or household pets
- Helical, 3.5 - 7.5 microns, 0.9 microns in diameter
- Prefers gastric antrum
- H. felis, H. fennelliae, H. cinaedi also associated with human disease
Treatment
- Same as H. pylori
Microscopic (histologic) description
- Long tight spirals; thicker and twice as long as H. pylori and usually visible with H&E stain
- Changes similar to but less severe than H. pylori gastritis (lymphoid aggregates, scant neutrophils)
Microscopic (histologic) images
Contributed by @liverwei and @DoktoraMalvar on Twitter
Helicobacter heilmannii
Helicobacter heilmannii
Positive stains
- H. pylori (polyclonal antibody cross-reacts, but not monoclonal antibody), Warthin Starry, Steiner, Diff-Quik
Additional references
Board review style question #1
A 16 year old boy presents with dyspepsia and abdominal pain. Endoscopy shows nodular mucosa and histology (shown above) shows gastritis with prominent lymphoid aggregates and organisms on the mucosal surface (inset). What is your diagnosis?
- Atrophic gastritis
- Autoimmune gastritis
- Eosinophilic gastritis
- H. heilmannii gastritis
- H. pylori gastritis
Board review style answer #1
