Cite this page: Weisenberg E. Granulomatous gastritis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stomachgranulomatousgastritis.html. Accessed December 23rd, 2024.
Definition / general
- Causes:
- Anisakiasis, common variable immunodeficiency, Crohn’s disease, foreign body, histoplasmosis, idiopathic, post-barium studies, sarcoidosis, tuberculosis, tumors (extravasated mucin), vasculitis
- Rarely Langerhans cell histiocytosis
- Idiopathic / isolated:
- Usually older white men vs. sarcoid (often young black men / women), other causes of granulomatous disease must be excluded
- Patients may later develop Crohn’s disease or sarcoidosis
- A descriptive diagnosis such as gastric mucosa with non-necrotizing granulomatous inflammation and a recommendation for followup may be more prudent than a diagnosis of idiopathic granulomatous gastritis
- Chronic granulomatous disease:
- May present with distinct or poorly formed granulomas in children with pigment-laded macrophages
- Associated with outlet obstruction (Am J Surg Pathol 1982;6:673)