Stomach
General
WHO classification
Author: Raul S. Gonzalez, M.D.
Editor-in-Chief: Debra L. Zynger, M.D.
Last author update: 10 December 2020
Last staff update: 22 February 2024
Copyright: 2020-2025, PathologyOutlines.com, Inc.
PubMed Search: WHO classification stomach
Cite this page: Gonzalez RS. WHO classification. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stomachWHOclassification.html. Accessed January 10th, 2025.
Definition / general
- WHO classification of tumors of the stomach
- Currently on 5th edition, published in 2019
- Based on histologic appearance, not molecular characteristics
WHO (2019)
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Benign epithelial tumors and precursors ICD-O codes
- Glandular intraepithelial neoplasia, low grade 8148/0
- Glandular intraepithelial neoplasia, high grade 8148/2
- Serrated dysplasia, low grade 8213/0
- Serrated dysplasia, high grade 8213/2
- Intestinal type dysplasia
- Foveolar type (gastric type) dysplasia
- Gastric pit / crypt dysplasia
- Intestinal type adenoma, low grade 8144/0
- Intestinal type adenoma, high grade 8144/2
- Sporadic intestinal type gastric adenoma
- Syndromic intestinal type gastric adenoma
- Adenomatous polyp, low grade dysplasia 8210/0
- Adenomatous polyp, high grade dysplasia 8210/2
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Malignant epithelial tumors ICD-O codes
- Adenocarcinoma, NOS 8140/3
- Tubular adenocarcinoma 8211/3
- Parietal cell carcinoma 8214/3
- Adenocarcinoma with mixed subtypes 8255/3
- Papillary adenocarcinoma, NOS 8260/3
- Micropapillary carcinoma, NOS 8265/3
- Mucoepidermoid carcinoma 8430/3
- Mucinous adenocarcinoma 8480/3
- Signet ring cell carcinoma 8490/3
- Poorly cohesive carcinoma 8490/3
- Medullary carcinoma with lymphoid stroma 8512/3
- Hepatoid adenocarcinoma 8576/3
- Paneth cell carcinoma
- Squamous cell carcinoma, NOS 8070/3
- Adenosquamous carcinoma 8560/3
- Carcinoma, undifferentiated, NOS 8020/3
- Large cell carcinoma with rhabdoid phenotype8014/3
- Pleomorphic carcinoma 8022/3
- Sarcomatoid carcinoma 8033/3
- Carcinoma with osteoclast-like giant cells8035/3
- Gastroblastoma 8976/1
- Neuroendocrine tumor, NOS 8240/3
- Neuroendocrine tumor, grade 1 8240/3
- Neuroendocrine tumor, grade 2 8249/3
- Neuroendocrine tumor, grade 3 8249/3
- Gastrinoma, NOS 8153/3
- Somatostatinoma, NOS 8156/3
- Enterochromaffin cell carcinoid 8241/3
- ECL cell carcinoid, malignant 8242/3
- Neuroendocrine carcinoma, NOS 8246/3
- Large cell neuroendocrine carcinoma 8013/3
- Small cell neuroendocrine carcinoma 8041/3
- Mixed neuroendocrine - nonneuroendocrine neoplasm (MiNEN) 8154/3
