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Inflammatory disorders

Lymphocytic enterocolitis

Author: Hanni Gulwani, M.B.B.S.

Last author update: 1 August 2012

Last staff update: 15 September 2020

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PubMed Search: Lymphocytic enterocolitis small bowel

Table of Contents

Definition / general | Microscopic (histologic) images | Lymphocytic colitis related

Cite this page: Gulwani H. Lymphocytic enterocolitis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/smallbowellymphocyticenterocolitis.html. Accessed December 25th, 2024.

Definition / general

Refractory sprue-like condition associated with colonic mucosal abnormalities (Can J Gastroenterol 2008;22:771)

Microscopic (histologic) images

Contributed by Hanni Gulwani, M.D.

Lymphocytic ileitis: ileal biopsy from 28 year old man with chronic diarrhea

Lymphocytic colitis related

High intraepithelial lymphocyte count in terminal ileum biopsies (Mod Pathol 2003;16:115, Am J Surg Pathol 2002;26:1484)
Normal range of ileal lymphocytes is 0 - 9 lymphocytes/100 enterocytes, decreases with age (Am J Clin Pathol 2007;127:816)
Lymphocytes are mostly suppressor T cells
Symptoms: chronic nonbloody diarrhea, relatively normal endoscopy

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