Skin nonmelanocytic tumor
Other tumors of skin
Endometriosis
Author: Christopher S. Hale, M.D.
Last author update: 1 September 2012
Last staff update: 14 July 2021
Copyright: 2001-2024, PathologyOutlines.com, Inc.
PubMed search: endometriosis [title] skin
Table of Contents
Definition / general | Case reports | Treatment | Gross description | Gross images | Microscopic (histologic) description | Microscopic (histologic) images | Positive stains | Negative stains | Differential diagnosisCite this page: Hale C. Endometriosis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/skintumornonmelanocyticendometriosis.html. Accessed December 22nd, 2024.
Definition / general
- This topic discusses features of cutaneous endometriosis only - a general discussion of endometriosis is found in the Ovary topic
- Ectopic endometrial tissue, usually described in pelvic organs, but 0.5% - 1.0% of cases are cutaneous
- Women of reproductive age, often due to iatrogenic seeding of umbilicus during C-section (Villar’s nodule) but may occur in almost any site
- Carcinoma rarely arises in preexisting endometriosis
- Women with endometriosis may have mildly increased risk of melanoma (Int J Epidemiol 2009;38:1143)
Case reports
- 35 year old woman with menstruating cutaneous lesion of umbilicus (J Med Case Reports 2009;3:9326)
- 37 year old woman with umbilical nodule (Dermatol Online J 2011;17:5)
Treatment
- Gonadotropin releasing hormone analogues
- Excision
Gross description
- Dark red to bluish nodule, may form cystic structure
Gross images
Images hosted on other servers:
Villar nodule
Microscopic (histologic) description
- Endometrial glands, endometrial stroma and hemorrhage
- May have marked decidual changes
Microscopic (histologic) images
Images hosted on other servers:
Endometriosis in periumbilical dermis
Various images
Negative stains
Differential diagnosis
- Sweat gland tumor
- Urachal duct cyst
- Pyogenic granuloma
- Hernia
- Residual embryonic tissue
- Primary or metastatic adenocarcinoma (Sister Joseph's nodule)
- Cutaneous endosalpingiosis
