Oral cavity & oropharynx
Benign epithelial tumors & processes
Multifocal epithelial hyperplasia
Author: Charu Thakral, M.D.
Last author update: 1 May 2013
Last staff update: 7 March 2023
Copyright: 2002-2024, PathologyOutlines.com, Inc.
PubMed Search: Multifocal epithelial hyperplasia[TIAB] oral cavity[mh]
Table of Contents
Definition / general | Case reports | Clinical images | Gross description | Microscopic (histologic) description | Microscopic (histologic) imagesCite this page: Thakral C. Multifocal epithelial hyperplasia. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/oralcavitymultifocalepithelialhyperplasia.html. Accessed November 27th, 2024.
Definition / general
- Also called Heck disease
- Discrete, recurrent papillary lesions on oral mucosa in Native American and Inuit children, associated with HPV 1, 13, 32 (Eur J Dermatol 2011;21:396)
Case reports
- 7 year old girl with HPV 32 related disease (J Maxillofac Oral Surg 2011;10:357)
Clinical images
Images hosted on other servers:
Slightly elevated
Multiple lesions
Lesions on tongue and lip
Gross description
- Well circumscribed, sessile and pale elevation of buccal mucosa
Microscopic (histologic) description
- Balloon cells in Malpighian layers, localized areas of mucosal epithelial hyperplasia with marked acanthosis and parakeratosis
Microscopic (histologic) images
Images hosted on other servers:
Parakeratosis
Typical nuclear changes
