Nasal cavity, paranasal sinuses, nasopharynx
Other nonneoplastic lesions
Nasal chondromesenchymal hamartoma
Author: Nat Pernick, M.D.
Last author update: 1 August 2004
Last staff update: 8 October 2020
Copyright: 2004-2025, PathologyOutlines.com, Inc.
PubMed Search: Nasal chondromesenchymal hamartoma
Table of Contents
Definition / general | Radiology images | Case reports | Treatment | Microscopic (histologic) description | Microscopic (histologic) images | Positive stains | Electron microscopy description | Additional referencesCite this page: Pernick N. Nasal chondromesenchymal hamartoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/nasalchondromes.html. Accessed April 2nd, 2025.
Definition / general
- Rare; intranasal and paranasal polypoid mass in infants and occasionally older children
- 2/3 male, mean age 14 months, range 1 day to 7 years
- Benign but fills nasal cavity and usually extends into ethmoid sinuses
- May erode bone, including cribriform plate and have an intracranial component
Radiology images
Contributed by I Weng Lao, M.D., Ph.D. and Jian Wang, M.D., Ph.D.
CT scan
Case reports
- 47 year old woman with endoscopic surgery for nasal polyp (Case of the Week #291)
Treatment
- Excision
Microscopic (histologic) description
- Well demarcated mature cartilage, myxoid stroma, focal osteoclast-like giant cells, aneurysmal bone cyst-like formations, spindle cells, collagen fibers
Microscopic (histologic) images
Contributed by I Weng Lao, M.D., Ph.D. and Jian Wang, M.D., Ph.D.
7 month old infant boy
Case #291
Various images
Electron microscopy description
- Fibroblastic and myofibroblastic differentiation
Additional references
