Mediastinum
Cystic lesions
Enteric (esophageal) duplication cyst
Author: Hanni Gulwani, M.B.B.S.
Last author update: 1 December 2012
Last staff update: 15 August 2022
Copyright: 2003-2024, PathologyOutlines.com, Inc.
PubMed Search: Enteric cyst
Table of Contents
Definition / general | Clinical features | Case reports | Gross description | Microscopic (histologic) descriptionCite this page: Gulwani H. Enteric (esophageal) duplication cyst. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/mediastinumentericcyst.html. Accessed December 27th, 2024.
Definition / general
- Children or teens, with cysts usually in posterior mediastinum, due to developmental defect from fusion of tracheoesophageal septum
- Gastric cysts may produce acid and rupture or hemorrhage
Clinical features
- Associated with vertebral anomalies (hemivertebrae, spina bifida)
- Leaky cysts are associated with pleural effusion or pulmonary consolidation
- Paraesophageal cysts are associated with dysphagia or subnormal weight gain
- Gastroesophageal cysts are associated with cough, vomiting, fever, pneumonia, empyema
Case reports
- 39 year old man with adenocarcinoma arising from a mediastinal enteric cyst (Intern Med 2007;46:781)
- Neonate with posterior mediastinal gastoenteric cyst (Saudi Med J 2004;25:955)
Gross description
- 2 - 10 cm, rounded or irregular, with fibromuscular wall of variable thickness
- Usually unilocular but may be multiloculated
- Smooth inner lining, often mucoid contents
Microscopic (histologic) description
- Squamous, simple columnar, pseudostratified columnar or mixed epithelial lining, usually with some gastric glandular mucosa, overlying a double layer of smooth muscle
- No cholesterol granulomas, no cartilage
