Lung
General
Grossing & features to report
Last author update: 1 September 2012
Last staff update: 10 May 2021
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histologic sampling lung tumors
Cite this page: Jain D. Grossing & features to report. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/lungtumorgrossing.html. Accessed December 25th, 2024.
Grossing
- 1 section per cm of tumor diameter, representative of grossly distinct areas
- Margins (bronchial, pulmonary artery / vein, visceral pleura, other surgical margins)
- Tumor and adjacent lung
- Tumor and bronchial wall
- Tumor and pleura
- Bronchial mucosa proximal to tumor
Frozen section
- May be difficult to distinguish:
- Touch preparation cytology recommended to supplement frozen section findings (J Clin Pathol 2010;63:675)
Features to report
Editor's note
Specimen type and site (involved bronchi or segments, laterality, intact or fragmented)
Procedure
Histologic type
Histologic grade (incorporating nuclear atypia, mitotic index)
Tumor size
Surgical resection margins (bronchi, peribronchial and perivascular soft tissue)
Involvement of bronchi, surfaces covering tumor (pleura, thoracic wall, diaphragm), adjacent structures
Angiolymphatic invasion
Presence of multiple tumors (intrapulmonary metastases)
Pleural dissemination
Lymph node involvement (site of lymph nodes, number obtained, number positive, size of largest metastasis, extracapsular invasion)
Presence of disease in uninvolved lung / bronchi
Presence of histologic treatment effect (if prior chemoradiation therapy)
Molecular studies, as appropriate
Features to report by organization:
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