Cite this page: Weisenberg E. Patterns of injury. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/lungnontumorpatternsofinjury.html. Accessed December 25th, 2024.
Definition / general
- Major categories of interstitial lung disease
- Fibrosing: UIP, NSIP, COP, lung disease with connective tissue disease, pneumoconiosis, drug reaction, radiation pneumonitis
- Granulomatous: sarcoidosis, hypersensitivity pneumonitis
- Eosinophilic
- Smoking related: DIP, respiratory bronchiolitis-associated interstitial lung disease
- Other: pulmonary alveolar proteinosis
- Source: Kumar et al.: Robbins and Cotran Pathologic Basis of Disease, 8th Edition, 2009
- Intraalveolar reaction: DIP, pulmonary alveolar proteinosis, infection, extrinsic allergic alveolitis, chronic eosinophilic pneumonia
- Small airway disease: bronchiolitis obliterans, respiratory bronchiolitis, mycoplasma infection, viral infection, extrinsic allergic alveolitis, eosinophilic pneumonia
- Large airway disease: allergic bronchopulmonary aspergillosis, bronchocentric granulomatosis, TB, fungi, Granulomatosis with polyangiitis (Wegener's)
- Granulomatous vasculitis: Granulomatosis with polyangiitis (Wegener's), sarcoidosis, Churg-Strauss, bronchocentric granulomatosis, fungi, TB
- Small vessel disease: primary pulmonary hypertension, thromboembolism, polyarteritis nodosa, veno-occlusive disease, Churg-Strauss syndrome
- Hemorrhage: Goodpasture's, SLE, immune complex glomerulonephritis, idiopathic pulmonary hemosiderosis, Granulomatosis with polyangiitis (Wegener's)
- Lymphoid infiltrates: lymphocytic interstitial pneumonia, lymphoma, lymphoid aggregates, extrinsic allergic alveolitis
- Eosinophils: chronic eosinophilic pneumonia, Churg-Strauss syndrome, bronchocentric granulomatosis, Langerhans cell histiocytosis
Additional references