Table of Contents
Definition / general | Case reports | Microscopic (histologic) description | Molecular / cytogenetics descriptionCite this page: Mihova D. t(5;14)(q31;q32); IGH::IL3. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/leukemiat514.html. Accessed December 18th, 2024.
Definition / general
- Diagnosis based on immunophenotype and genetic findings, even with low blast count
- Very rare; < 1% of all ALL; both children and adults (Blood 1989;73:2081)
- Presents with variable eosinophilia; may be asymptomatic and lack any blasts (Medicine (Baltimore) 1990;69:232)
Case reports
- 13 year old boy with cardiac disease (BMJ Case Rep 2012 Jan 20;2012)
- CD10+ acute leukemia with t(5q;14q) translocation and hypereosinophilia (Acta Haematol 1989;82:85)
Microscopic (histologic) description
- CD19+ CD10+ lymphoblasts with circulating reactive eosinophils
Molecular / cytogenetics description
