Colon
Other nonneoplastic
Apoptotic colopathy
Author: Hanni Gulwani, M.B.B.S.
Last author update: 1 May 2013
Last staff update: 3 May 2022
Copyright: 2003-2024, PathologyOutlines.com, Inc.
PubMed Search: Colon [title] bowel preparation
Cite this page: Gulwani H. Apoptotic colopathy. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/colonbowelprep.html. Accessed December 23rd, 2024.
Microscopic (histologic) description
- Reduced intracellular mucin, epithelial apoptosis and sloughing, increase in mitotic figures (Hum Pathol 1998;29:972, Cesk Patol 2011;47:130)
- May have erosion of superficial epithelium, consistent with clinical impression of aphthoid ulcer
- Also increased lymphocytes and neutrophils (Dis Colon Rectum 2006;49:109)
- Patchy mononuclear infiltration in upper part of lamina propria, increased epithelial cell proliferation of individual crypts, basal cryptitis (Cesk Patol 2010;46:37)
- Rarely lamina propria edema or extravasated red blood cells
Differential diagnosis
