Cite this page: Mansouri J. Features to report & grossing. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/appendixfeatures.html. Accessed December 26th, 2024.
Features to report
- Tumor size
- Histologic type
- Histologic grade
- Depth of invasion
- Angiolymphatic invasion
- Perineural invasion
- Margin involvement (surgical, radial, mesenteric)
- Peritumoral satellite nodules (for appendiceal carcinomas)
- Lymph node involvement (total involved, total examined)
- Mitotic rate and Ki-67 labeling index (for appendiceal carcinoids)
- Additional findings such as diverticula
- As of June 2012, there are updated College of American Pathologists (CAP) protocols for both appendiceal adenocarcinomas and well-differentiated neuroendocrine tumors (NET) of the appendix: visit CAP.org and search for "Cancer Protocols and Checklists"
- Staging for NETS does not include poorly differentiated (high-grade, G3) neuroendocrine carcinomas, small cell carcinomas, and goblet cell carcinoids (use CAP protocol for appendiceal carcinomas)
Grossing
- Describe length and greatest diameter, external surface (fibrinous exudate, perforation), luminal patency, mucosa, details of any unusual lesions
- Submit longitudinal or cross section of distal tip (common site of carcinoid tumors), cross sections from middle and margin of resection
