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Bone marrow nonneoplastic


Last staff update: 4 April 2024

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Related chapters: Bone marrow neoplastic, Hematology, Lymphoma & related disorders, Lymph nodes and spleen, nonlymphoid

Editorial Board oversight: Anamarija M. Perry, M.D. (last reviewed November 2023)
Table of contents
General:biopsy and aspirate smear books embryonic development features to report routine stains
Normal:general age related changes basophils eosinophils erythroid maturation (erythropoiesis) hematogones lymphocyte maturation mast cells megakaryocytes monocytes neutrophil maturation osteoblasts osteoclasts plasma cells
Alterations in cellularity:amegakaryocytosis aplastic anemia (AA) congenital dyserythropoietic anemia (CDA) (pending) congenital marrow failure (pending) Diamond-Blackfan anemia dyskeratosis congenita Fanconi anemia hypercellularity neutropenia (pending) pure red cell aplasia Shwachman-Diamond syndrome thrombocytopenia absent radii (TAR) syndrome
Benign changes:arsenic toxicity autoimmune myelofibrosis (AIMF) gelatinous transformation iron in nonneoplastic marrow lymphoid aggregates (benign) megaloblastic anemia necrosis plasmacytosis polymorphous reactive lymphoid hyperplasia systemic polyclonal B immunoblastic proliferation
Infectious / inflammatory:CMV cryptococcus granulomatous inflammation histoplasmosis HIV / AIDS parvovirus (erythrovirus) B19 q fever
Noninfectious systemic disorders:alcohol abuse bone marrow transplantation Chédiak-Higashi syndrome chronic renal disease (pending) copper deficiency hemophagocytic lymphohistiocytosis Pearson syndrome
Storage-type histiocytosis:Gaucher disease Niemann-Pick disease sea blue histiocytosis (syndrome) uncommon storage diseases
Immunostains: CD34 CD41 CD61 CD68 CD117 CMV E-cadherin hemoglobin A   myeloperoxidase parvovirus B19

Special stains: AFB GMS iron PAS reticulin trichrome

Superpages: entire chapterimagesvirtual slides
Index (Alphabetical table of contents)
A-E:age related changes alcohol abuse amegakaryocytosis aplastic anemia (AA) arsenic toxicity autoimmune myelofibrosis (AIMF) basophils biopsy and aspirate smear bone marrow transplantation chronic renal disease (pending) Chédiak-Higashi syndrome CMV congenital dyserythropoietic anemia (CDA) (pending) congenital marrow failure (pending) copper deficiency cryptococcus Diamond-Blackfan anemia dyskeratosis congenita embryonic development eosinophils erythroid maturation (erythropoiesis)
F-N:Fanconi anemia features to report Gaucher disease gelatinous transformation general granulomatous inflammation hematogones hemophagocytic lymphohistiocytosis histoplasmosis HIV / AIDS hypercellularity iron in nonneoplastic marrow lymphocyte maturation lymphoid aggregates (benign) mast cells megakaryocytes megaloblastic anemia monocytes necrosis neutropenia (pending) neutrophil maturation Niemann-Pick disease
O-Z:osteoblasts osteoclasts parvovirus (erythrovirus) B19 Pearson syndrome plasma cells plasmacytosis polymorphous reactive lymphoid hyperplasia pure red cell aplasia q fever routine stains sea blue histiocytosis (syndrome) Shwachman-Diamond syndrome systemic polyclonal B immunoblastic proliferation thrombocytopenia absent radii (TAR) syndrome uncommon storage diseases
Bone marrow nonneoplastic books

Cherry: 2022

Foucar: 2009

Foucar: 2017

Foucar: 2023

Hsi: 2017

Hudnall: 2019

IARC: 2017

Jaffe: 2016

Naeim: 2018

Wake: 2023

Wang: 2020



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