Transfusion medicine
Transfusion transmitted disease
Bacterial contamination in pRBC products

Author: Huy Phu Pham, M.D. (see Authors page)

Revised: 30 October 2017, last major update September 2011

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: pRBC bacterial contamination

Cite this page: Pham, H.P. Bacterial contamination in pRBC products . PathologyOutlines.com website. http://pathologyoutlines.com/topic/transfusionmedbacteriaprbc.html. Accessed November 18th, 2017.
Definition / general
  • Rate of bacterial contamination in packed RBCs (pRBCs) is 2.6 in 100,000 pRBCs transfused and the rate of septic transfusion reaction is 1 in 250,000 products
  • Risk of death is 1 per 8 million units
  • Most bacteria is not viable at storage temperature
  • Associated with high mortality rate
  • Yersinia enterocolitica is responsible for 60% of reported cases of RBC associated sepsis; 70% are fatal