Thyroid gland
Thyroiditis
Silent thyroiditis

Author: Shahidul Islam, M.D., Ph.D. (see Authors page)

Revised: 13 January 2017, last major update March 2009

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PubMed Search: silent thyroiditis
Cite this page: Silent thyroiditis. PathologyOutlines.com website. http://pathologyoutlines.com/topic/thyroidsilentthyroiditis.html. Accessed May 24th, 2017.
Definition / general
  • Transient, painless hyperthyroidism that spontaneously resolves
Terminology
  • Also called painless or sometimes chronic lymphocytic thyroiditis
Epidemiology
  • Relatively uncommon; usually women
Etiology
  • Cause unknown, although hyperfunction is due to destruction of thyroid follicles
Clinical features
Laboratory
  • Elevated T3 / T4, low radioactive iodine uptake
Case reports
Treatment
  • Usually none, beta blockers possibly in hyperthyroid phase
Gross description
  • Diffuse goiter or slightly enlarged thyroid gland
Microscopic (histologic) description
  • Preserved lobular pattern with follicular destruction, variable lymphocytic infiltrate, rare / no oncocytic change, no / focal fibrosis
  • T cells present in paracortex, B cells predominate in germinal center
Microscopic (histologic) images

Images hosted on other servers:

Mild lymphocytic infiltrate (Fig 1b)

Differential diagnosis