Thyroid & parathyroid

Other thyroid malignancies

Plasmacytoma



Last author update: 1 July 2015
Last staff update: 11 January 2023

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PubMed Search: Plasmacytoma thyroid

Note: Plasmacytoma is described in detail at Bone marrow neoplastic - Plasmacytoma; this topic only describes features specific to the thyroid gland

Sheren Younes, M.D., Ph.D.
Page views in 2024 to date: 153
Cite this page: Younes S. Plasmacytoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/thyroidplasmacytoma.html. Accessed March 29th, 2024.
Definition / general
  • Rare tumor of thyroid gland, presenting as a mass
  • Solitary or associated with multiple myeloma
  • Diagnosis should be restricted to tumors without a lymphoid component
Case reports
Gross images

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Gray, firm, fleshy

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Thyroidectomy specimen

Microscopic (histologic) description
Microscopic (histologic) images

Case #394

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CD79a

CD138

Kappa

Lambda



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Mature and immature plasma cells

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H&E, CD138+

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(A) Kappa light chain+
(B) Lambda light chain-

Cytology description
Cytology images

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Intranuclear inclusion

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Congo red+

Positive stains
Negative stains
Differential diagnosis
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