Thyroid gland
Thyroiditis
Lithium thyroiditis

Author: Shahidul Islam, M.D., Ph.D. (see Authors page)

Revised: 12 January 2017, last major update March 2009

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PubMed Search: lithium thyroiditis
Cite this page: Lithium thyroiditis. PathologyOutlines.com website. http://pathologyoutlines.com/topic/thyroidlithiumthyroiditis.html. Accessed August 20th, 2017.
Definition / general
  • Lithium directly damages thyroid follicular cells, which releases thyroglobulin, which may be hydrolyzed to thyroxine, causing hyperthyroidism
Case reports
Microscopic (histologic) description
  • Small follicles with atrophy and minimal colloid; follicles contain desquamated follicular cells, macrophages and multinucleated giant cells; some giant cells contain birefringent calcium oxalate crystals (J Clin Pathol 1995;48:582)
Microscopic (histologic) images

Images hosted on PathOut server:

Case of the Week #139

Differential diagnosis