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Thyroid gland
Benign neoplasms
Hyalinizing trabecular neoplasm

Reviewer: Shahidul Islam, M.D., Ph.D. (see Reviewers page)
Revised: 10 June 2013, last major update March 2009
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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Case reports
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Gross description
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Gross images
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Lobular with white, shiny, cartilaginous elements (AFIP)
Micro description
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Micro images
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Encapsulated tumor with cells in nests and hyalinized stroma
Spindle cells in trabecular pattern, separated by thin fibrovascular septa
Cells have enlarged nuclei with vesicular chromatin
Various images
See Fig. 7-14
Contributed by Dr. Mark R. Wick
Images from AFIP:
Twisting trabeculae
Prominent nesting
Nuclear grooves (arrows) and pseudoinclusions (arrowhead)
Psammoma body
Intraluminal and cytoplasmic thyroglobulin (AFIP)
Other tumors that appear similar:
Trabecular variant of papillary carcinoma
Large cytoplasmic bodies in other tumors
Cytology description
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Cytology images
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Elongated tumor with acellular stroma
Positive stains
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Negative stains
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Molecular / cytogenetics description
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Differential diagnosis
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End of Thyroid gland > Benign neoplasms > Hyalinizing trabecular neoplasm


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