Testis and epididymis
Non-neoplastic lesions
Vasitis nodosa

Author: Rafael Jimenez, M.D. (see Authors page)

Revised: 25 May 2017, last major update March 2012

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PubMed Search: vasitis nodosa

Cite this page: Vasitis nodosa. PathologyOutlines.com website. http://pathologyoutlines.com/topic/testisvasitisnodosa.html. Accessed July 24th, 2017.
Definition / general
  • Granulomatous condition of vas deferens that resembles spermatic granuloma of epididymis
  • Usually post vasectomy or herniorrhaphy
  • Occasionally associated with recanalization
Microscopic (histologic) description
  • Proliferating ductules and dilated tubules containing spermatozoa in wall of vas deferens
  • Also associated with small bundles of hyperplastic smooth muscle
  • Vas deferens may show irregular thickening
  • Ductules may connect with vas deferens (like diverticula or salpingitis isthmica nodosa but with inflammation and less smooth muscle hypertrophy)
  • May see perineural or vascular invasion by proliferating ductules
Microscopic (histologic) images

Images hosted on other servers:

Sperm granuloma

Extravasated spermatozoa

Atypical nuclei


Nodular enlargement

Sperm granulomas

Proliferating ductules

Differential diagnosis