Testis and epididymis
Nonneoplastic testicular lesions

Authors: Rafael Jimenez, M.D., Sean Williamson, M.D. (see Authors page)

Revised: 24 July 2017, last major update December 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Spermatocele

Cite this page: Spermatocele. PathologyOutlines.com website. http://pathologyoutlines.com/topic/testisspermatocele.html. Accessed November 23rd, 2017.
Definition / general
  • Cystic dilation of rete testis or head of epididymis, often in efferent ducts
Microscopic (histologic) description
  • Lined by cuboidal or flattened epithelium, often cilia can be identified
  • Thin connective tissue wall, no smooth muscle
  • Cysts usually translucent
  • Lumen contains spermatozoa and proteinaceous fluid
  • Associated with foreign body giant cell reaction, cholesterol clefts
Microscopic (histologic) images

Images hosted on other servers:

Flattened epithelial cells

Numerous spermatozoa

Differential diagnosis
  • Hydrocele: mesothelial lining, lumen does not contain spermatozoa