Testis and epididymis
Nonneoplastic testicular lesions
Radiation effect

Author: Sean Williamson, M.D. (see Authors page)

Revised: 7 April 2017, last major update December 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: "radiation effect" testicular

Table of Contents
Definition / general
Cite this page: Radiation effect. PathologyOutlines.com website. http://pathologyoutlines.com/topic/testisradiation.html. Accessed June 22nd, 2017.
Definition / general
  • Germ cells have variable sensitivity to radiation - type B spermatogonia are most sensitive, spermatids are least sensitive
  • Therapeutic radiation may cause only temporary infertility with recovery in 30 - 80 weeks, delayed if combined with chemotherapy
  • Radiation for intratubular germ cell neoplasia causes germ cell aplasia
  • Radiation exposure at Hiroshima and Nagasaki, Japan in 1945 caused increased tubular sclerosis, vascular hyalinization