Testis and epididymis
Paratesticular tumors
Mucinous adenocarcinoma

Author: Jennifer Gordetsky, M.D. (see Authors page)

Revised: 19 June 2017, last major update January 2014

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed Search: Mucinous adenocarcinoma testis
Cite this page: Mucinous adenocarcinoma. PathologyOutlines.com website. http://pathologyoutlines.com/topic/testismucincystadenoca.html. Accessed October 20th, 2017.
Definition / general
  • Ovarian type surface epithelial carcinoma of the testis with mucinous differentiation
Epidemiology
  • Extremely rare testicular tumor reported in middle age and elderly men (mean age 62)
Pathophysiology
  • The histogenesis of the ovarian type surface epithelial tumors of the testis and paratestis remains unclear
  • These tumors are possibly derived from Müllerian remnants or by metaplasia of the mesothelium of the tunica vaginalis (Hum Pathol 2011;42:1343)
Diagnosis
  • Clinical evaluation is necessary to rule out metastatic spread from a primary adenocarcinoma of the appendix, colon, stomach, pancreas, lung or prostate
Case reports
Treatment
  • Radical orchiectomy
Clinical images

Images hosted on other servers:

Right testicular borderline mucinous tumor

Gross description
  • Mucinous, cystic mass replacing the testicular parenchyma
Microscopic (histologic) description
  • Well to moderately differentiated malignant cystic neoplasm with mucinous differentiation
  • Back to back irregular glands, elongated fine complex papillary structures lined with alternating goblet cells and ciliated cells, with little intervening stroma
  • Papillary structures have atypical cells with hyperchromatic overlapping elongated nuclei with coarse chromatin and increased nuclear to cytoplasmic ratio
  • Cystic spaces filled with mucin, fibrinopurulent material, degenerative cellular debris
  • Psammomatous calcifications can be present as well as mucin extravasation
Microscopic (histologic) images

Images hosted on other servers:

Cyst wall irregularly
thickened
and fibrotic

Mutinous epithelium
resembling endocervical
type cells

Positive stains
Negative stains
Differential diagnosis