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Testis and epididymis
Sex cord stromal tumors
Leydig (interstitial) cell tumors

Reviewer: Swapnil U. Rane, M.D. (see Reviewers page)
Revised: 30 July 2013, last major update July 2013
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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Terminology
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Epidemiology
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Sites
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Pathophysiology
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Etiology
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Clinical features
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Radiology
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Case reports
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Treatment
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Prognosis
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Gross description
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Gross images
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Leydig cell tumor

Micro description
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Micro images
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Sheets of large polygonal cells

Nodular aggregates of tumor cells

High power

With nodules of vacuolated cells

With marked nuclear atypia


Inhibin+

Cytokeratin+

Various images

Metastases to perirenal fat



Case of the Week #122:

Inhibin



Contributed by Dr. Mowafak Hamodat, Eastern Health of Newfoundland and Labrador, St. John's, Canada:

Pan-keratin


Calretinin

Inhibin

Synaptophysin

Vimentin



Contributed by Dr. Kristine Cornejo, University of Massachusetts Medical Center:

4x H&E

10x H&E

20x H&E

40x H&E

40x Reinke crystalloid


Inhibin

Mart1

Melan-A

Pan-keratin

PLAP

Cytology description
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Cytology images
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Reinke's crystalloid

Reinke's crystalloid: alcohol fixed smears

Case of the Week #122

Positive stains
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Negative stains
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Electron microscopy description
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Molecular / cytogenetics description
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Differential diagnosis
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End of Testis and epididymis > Sex cord stromal tumors > Leydig (interstitial) cell tumors


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