Testis and epididymis
Infectious testicular lesions

Author: Sean Williamson, M.D. (see Authors page)

Revised: 5 April 2017, last major update December 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: testicular lesions AIDS

Table of Contents
Definition / General
Cite this page: AIDS. PathologyOutlines.com website. http://pathologyoutlines.com/topic/testisAIDS.html. Accessed April 23rd, 2017.
Definition / General
  • Associated with markedly reduced spermatogenesis, arrested maturation, germ cell aplasia, tubular hyalinization / thickening of basement membranes, interstitial inflammation and fibrosis, reduction in Leydig cells, Sertoli cell only pattern (J Pathol 1991;163:47, Urology 1999;53:203, Mod Pathol 1989;2:233, Hum Pathol 1989;20:210)
  • Often other infections in testis or epididymis (Candida, CMV, Histoplasma, mycobacteria, toxoplasmosis)
  • Testicular atrophy related findings do not appear to be immune mediated (Hum Pathol 1989;20:572)
  • Testis is an uncommon location for Kaposi sarcoma in AIDS patients