Stomach
Polyps
Juvenile polyp
Author: Elliot Weisenberg, M.D.
Last author update: 1 August 2012
Last staff update: 1 September 2020
Copyright: 2003-2024, PathologyOutlines.com, Inc.
PubMed Search: gastric juvenile polyp
Table of Contents
Definition / general | Gross description | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosisCite this page: Weisenberg E. Juvenile polyp. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stomachjuvenile.html. Accessed April 26th, 2024.
Definition / general
- Also called retention polyp
- Part of generalized juvenile polyposis coli or rare gastric subtype, 20 - 50% of patients with syndrome have gastric polyps
- Syndrome due to genetic dysregulation of TGF-β pathway
- Associated with increased risk of colorectal and gastric carcinoma
Gross description
- Smooth surfaced, 1 - 2 cm, short narrow stalk
Microscopic (histologic) description
- Irregular cysts in lamina propria with normal gastric epithelium
- Surface and foveolar hyperplasia, may have stromal hemorrhage, surface ulceration and chronic inflammation due to torsion
Microscopic (histologic) images
Image hosted on other server:
Gastric juvenile polyp
Differential diagnosis
- Hyperplastic polyp: usually background mucosal disease, may need clinical or family history for definitive diagnosis
