Table of ContentsDefinition / general | Microscopic (histologic) description | Differential diagnosis | Additional references
Cite this page: Graft versus host disease. PathologyOutlines.com website. http://pathologyoutlines.com/topic/stomachGVHD.html. Accessed July 20th, 2017.
Definition / general
- Common after allogeneic bone marrow transplantation, although diagnosis based on subtle findings
- Similar histology associated with common variable immunodeficiency and X-linked agammaglobulinemia (Am J Surg Pathol 1996;20:1240)
Microscopic (histologic) description
- Apoptosis, gland destruction, sparse inflammatory infiltrate, granular eosinophilic debris in dilated glands ("exploding crypt cell", 94% specific, 41% sensitive, Am J Surg Pathol 1997;21:1037)
- CMV, HIV