Stains
N-myc

Author: Nat Pernick, M.D. (see Authors page)

Revised: 16 November 2015, last major update June 2005

Copyright: (c) 2002-2015, PathologyOutlines.com, Inc.

PubMed Search: N-myc [title]

Table of Contents
Definition / general
Cite this page: N-myc. PathologyOutlines.com website. http://pathologyoutlines.com/topic/stainsnmyc.html. Accessed May 27th, 2017.
Definition / general
  • Also called MYCN, gene at 2p24
  • Amplified gene forms double minutes and homogenously staining regions, and produces excessive N-myc protein
  • Neuroblastoma:
    • Amplification (>10 copies by Southern blot or FISH) associated with poor prognosis and 1p36.3 deletions