Stains
IL8

Author: Nat Pernick, M.D. (see Authors page)

Revised: 20 November 2015, last major update August 2014

Copyright: (c) 2003-2014, PathologyOutlines.com, Inc.

PubMed Search: IL-8[title], CXCL8[title]

Cite this page: IL8. PathologyOutlines.com website. http://pathologyoutlines.com/topic/stainsil8.html. Accessed November 22nd, 2017.
Definition / general
  • Proinflammatory and pro-angiogenic chemokine
  • Produced by endothelial cells, epithelial cells, goblet cells (Clin Exp Allergy 2014;44:540), macrophages, mesothelial cells, smooth muscle cells in airways (Wikipedia) and various tumor cells (see below)
  • Also known as CXCL8
Pathophysiology
Clinical features
Uses by pathologists
  • No definite uses at this time
Microscopic (histologic) images

Cervical cancer

Positive staining - normal
  • Endothelial cells, epithelial cells, goblet cells, macrophages, mesothelial cells, smooth muscle cells in airways
Positive staining - malignant