Stains
Factor VIII related antigen

Author: Nat Pernick, M.D. (see Authors page)

Revised: 16 December 2015, last major update July 2012

Copyright: (c) 2003-2015, PathologyOutlines.com, Inc.

PubMed Search: Factor VIII related antigen
Cite this page: Factor VIII related antigen. PathologyOutlines.com website. http://pathologyoutlines.com/topic/stainsfactorviii.html. Accessed October 19th, 2017.
Definition / general
  • Interpretation: cytoplasmic stain; endothelium acts as a positive internal control
Uses by pathologists
  • Common endothelial marker
Microscopic (histologic) images

Images hosted on other servers:

Capillary hemangioma of endometrium (fig 2B)


Cribriform DCIS of breast - fig 2a: factor VIII staining shows only rare vascular proliferation; 2b: low MIB1 staining

Positive staining - normal
  • Endothelial cells, megakaryocytes, platelets and mast cells
Positive staining - disease
  • Vascular tumors