Stains
Cytokeratin AE1

Author: Nat Pernick, M.D. (see Authors page)

Revised: 11 December 2015, last major update October 2013

Copyright: (c) 2003-2015, PathologyOutlines.com, Inc.

PubMed Search: AE1[title]
Cite this page: Cytokeratin AE1. PathologyOutlines.com website. http://pathologyoutlines.com/topic/stainsae1.html. Accessed May 27th, 2017.
Definition / general
  • Usually used in a cytokeratin cocktail with AE3 (see AE1/AE3)
  • Detects high molecular weight CK10, CK14, CK15 and CK16 and low molecular weight CK19; these are acidic (type I) cytokeratins
Uses by pathologists
Positive staining - normal
Positive staining - disease
Negative staining
Microscopic (histologic) images

Images hosted on other servers:

Liver-bile ducts in severe acute
rejection with dense lymphoid
infiltrate: H&E (top), AE1 (bottom)


Liver-bile ducts in chronic rejection with dense lymphoid infiltrate: H&E (top), AE1 (bottom)