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Extraskeletal osteosarcoma


Vijay Shankar, M.D.

Last author update: 1 November 2012
Last staff update: 6 January 2022

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PubMed Search: Extraskeletal osteosarcoma [title]

Vijay Shankar, M.D.
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Table of Contents
Definition / general | Case reports | Clinical images | Gross images | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosis
Cite this page: Shankar V. Extraskeletal osteosarcoma. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/softtissueeskosteo.html. Accessed April 23rd, 2024.
Definition / general
  • Adults, extremities
  • May occur after Xray exposure
  • 60% mortality, worse than chondrosarcoma
  • Subtypes: osteoblastic, chondroblastic, fibroblastic, MFH-like, telangiectactic, well-differentiated (parosteal)
Case reports
Clinical images

Contributed by Mark R. Wick, M.D.
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Upper arm x-ray



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Skin of lower abdomen

Gross images

Case #370

Case #1: 75 year old man

 

Case #2: 55 year old woman



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Retroperitoneal mass

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Upper arm mass

Microscopic (histologic) description
  • Osteoid and bone formation produced by tumor cells, without interposition of cartilage
Microscopic (histologic) images

Case #370 - Case #1

CK negative

 

Vimentin positive



Case #370 - Case #2:

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400x



Contributed by Mark R. Wick, M.D.
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Upper arm



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Cutaneous tumor on scar of previous bone graft

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Upper arm



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Chest wall

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Retroperitoneal mass

Differential diagnosis
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