Small bowel (small intestine)
Infectious disorders
Strongyloides stercoralis

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 30 October 2017, last major update August 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Strongyloides stercoralis [title] small bowel

Cite this page: Gulwani, H. Strongyloides stercoralis. PathologyOutlines.com website. http://pathologyoutlines.com/topic/smallbowelstrongyloides.html. Accessed November 18th, 2017.
Definition / general
  • Nematode with complex life cycle that alternates between free living and parasitic cycles, with potential for autoinfection and multiplication within host
Life cycle
  • Larvae burrow into mucosa of duodenum and jejunum, where they mature into adults
  • Females lay eggs, which develop into larvae that pass into stool, where they mature and become infective
  • Infective larvae in soil penetrate intact skin, usually through feet
  • Larvae enter circulatory system, are transported to lungs, enter alveolar spaces, are carried to trachea and pharynx, are swallowed and enter intestinal tract, where process is repeated
  • If larvae become infective before leaving body, they may invade intestinal mucosa or perianal skin, causing autoinfection
Diagrams / tables

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Life Cycle

Clinical features
  • Symptoms: none, diarrhea, malabsorption
  • Severe / fatal infections in immunocompromised, due to worms moving from GI tract into other organs (WormBook 2007:1)
Diagnosis
  • Larvae in stool
  • Adult female or eggs in small bowel mucosa, often with eosinophilic or granulomatous inflammation
Case reports
Treatment
Microscopic (histologic) images

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Images contributed by Dr. Josehp Christopher Castillo, Institute of Anatomical Pathology Arias Stella, Peru

Small intestine



Case of the Week #133

Various images



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Various images

Virtual slides

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Small intestine

Additional references