Skin - Nonmelanocytic tumors
Premalignant or noninvasive
Bowenoid papulosis

Author: Christopher Hale, M.D. (see Authors page)

Revised: 13 October 2016, last major update June 2012

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Bowenoid papulosis

Cite this page: Bowenoid papulosis. PathologyOutlines.com website. http://pathologyoutlines.com/topic/skintumornonmelanocyticbowenoidpapulosis.html. Accessed May 22nd, 2017.
Definition / general
  • Multiple pigmented papular lesions of anogenital area, usually in young adults, resembling condyloma acuminatum
  • May regress spontaneously
  • Almost never invasive
Case reports
Clinical images

Images hosted on other servers:

Penile shaft

Gross description
  • Flat papules on anogenital skin
Microscopic (histologic) description
  • Resembles carcinoma in situ, but with localized acanthosis similar to condylomas
  • Low power view is “salt and pepper” due to dark nuclei and clear vacuolar cytoplasm
  • Usually no adnexal involvement
Microscopic (histologic) images

Images hosted on other servers:

Acanthosis and dyskeratosis

Positive stains
Molecular / cytogenetics description
  • HPV type 16 is most common
Differential diagnosis