Skin - Nonmelanocytic tumors
Adnexal tumors - eccrine sweat glands
Aggressive digital papillary adenoma

Author: Christopher Hale, M.D. (see Authors page)

Revised: 6 October 2016, last major update June 2012

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PubMed Search: Aggressive digital papillary adenoma

Cite this page: Aggressive digital papillary adenoma. PathologyOutlines.com website. http://pathologyoutlines.com/topic/skintumornonmelanocyticaggressivedigital.html. Accessed August 17th, 2017.
Definition / general
  • Also called digital papillary eccrine adenoma
  • Usually digits
  • Recurs locally
  • Histologic criteria not reliable for distinguishing from digital papillary adenocarcinoma (Modern Pathol 2006;19:S93)
  • Malignant counterpart has poor glandular differentiation, necrosis, atypia, invasion
  • Metastasizes to lung in many cases
Case reports
Microscopic (histologic) description
  • Tubuloalveolar and ductal structures
  • Also areas of papillary projections protruding into lumina (may resemble breast carcinoma)
Positive stains
Differential diagnosis