Skin - Nonmelanocytic tumors
Lymphoma and related disorders
NK / T cell lymphoma, extranodal, nasal type

Author: Christopher Hale, M.D. (see Authors page)

Revised: 11 October 2016, last major update July 2012

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed search: NK/T cell lymphoma [title] nasal

Cite this page: NK / T cell lymphoma, extranodal, nasal type. PathologyOutlines.com website. http://pathologyoutlines.com/topic/skintumornonmelanocyticNKTcell.html. Accessed October 18th, 2017.
Definition / general
  • Aggressive tumors, usually in GI tract, less commonly in skin
  • More common in Asia and South American than Western countries
  • Estimated 5 year survival: 0%
Case reports
Clinical images
Images hosted on PathOut server:

Courtesy of Dr. Mark R. Wick

Microscopic (histologic) description
  • May involve epidermis, dermis or subcutis
  • Polymorphous lymphoid infiltrate with eosinophils, plasma cells, histiocytes
  • Lymphocytes are usually large pleomorphic cells with vesicular nuclei and prominent nucleoli
  • Also medium or small with irregular nuclei
  • Usually angiocentric (52%) with necrosis (62%)
  • Apoptosis common
  • Occasionally clear cytoplasm
Microscopic (histologic) images
Images hosted on PathOut server:


CD56

CD57

EBV in situ hybridization



Images hosted on other servers:

Tumor from various sites, including skin

Positive stains
Negative stains