Author: Nat Pernick, M.D., PathologyOutlines.com, Inc.
Revised: 4 July 2009, last major update November 2008
Copyright: (c) 2005-2009, PathologyOutlines.com, Inc.
● Plural - ephelides
● Affects sun exposed areas of skin of susceptible individuals (fair skin type and red hair)
● Appears in early childhood; fades in winter and reappears in summer
● Risk factor for skin cancer
● Due to variations in melanocortin-1-receptor gene (Hum Mol Genet 2001;10:1701)
Face Face and upper body
● Mild hyperpigmentation of basal keratinocytes, normal architecture
End of Skin-Melanocytic Tumors > Ephelis (freckle)
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