Skin-nontumor / Clinical Dermatology
Reviewer: Mowafak Hamodat MB.CH.B, MSc., FRCPC, Eastern Health, St. Johns (Canada) (see Reviewers page)
Revised: 22 March 2011, last major update March 2011
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.
● Secondary lesions occur on face and trunk; are maculopapular and resemble drug eruption, lichen planus and psoriasis
● May present as moth-eaten alopecia on scalp, mucous patches on tongue
● Diagnose by serology
● Scaly, flesh-colored to erythematous papules or annular plaques
● Copper macules on palms and soles
● Dense perivascular or diffuse plasma cell infiltrate with marked endothelial swelling and proliferation in blood vessels
● May have noncaseating granulomas, vacuolar interface change, acanthosis, spongiosis or lymphocyte exocytosis
● Steiner stain (71% sensitive)
End of Skin-nontumor / Clinical Dermatology > Infectious disorders > Syphilis
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