Skin-nontumor / Clinical dermatology
Other dermatoses
Synovial metaplasia

Author: Mowafak Hamodat, M.D., MB.CH.B, MSc., FRCPC (see Authors page)

Revised: 21 July 2016, last major update August 2011

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PubMed Search: Synovial metaplasia

Cite this page: Synovial metaplasia. PathologyOutlines.com website. http://pathologyoutlines.com/topic/skinnontumorsynovialmetaplasia.html. Accessed December 7th, 2016.
Definition / General
  • Metaplastic changes resembling synovium in non-joint spaces, usually in patients with prior surgery or traumatic injuries
  • Synovial-type membranes may form against surface of suture material, tissue expanders or implants
  • Associated with movement, loose areolar tissue that would develop spaces secondary to movement, and relatively smooth gliding surfaces that can resist penetration by fibroblasts (Arch Pathol Lab Med 2002;126:727)
  • Membranes resemble joint (“true”) synovial membranes
  • May be associated with cyst formation and transepidermal fistulae (Am J Surg Pathol 1987;11:343)
Clinical Features
  • Resemble suture granulomas
Micro Description
  • Resembles hyperplastic synovium
Micro Images

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Various images

Positive Stains
Negative Stains