Skin-nontumor / Clinical Dermatology
Reviewer: Mowafak Hamodat MB.CH.B, MSc., FRCPC, Memorial University of Newfoundland (see Reviewers page)
Revised: 24 August 2011, last major update August 2010
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.
● Difficult to see with H&E or special stains
● Concentrated in skin of digits, finger pads, proximal nail folds, palms, dorsum of feet, lips, hard palate
● More common in outer root sheath of hair follicles and tactile hair discs
Skin and Merkel cells
● NSE, neurofilament, keratin
● Dense core neurosecretory-type granules in cytoplasm beneath cell membrane or within unmyelinated neurites
● Anchored to adjacent keratinocytes by spinous processes
End of Skin-nontumor / Clinical Dermatology > General > Merkel cells
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