Skin-nontumor / Clinical dermatology
Other dermatoses
Lichenoid dermatitis

Author: Mowafak Hamodat, M.D., MB.CH.B, MSc., FRCPC (see Authors page)

Revised: 15 July 2016, last major update August 2011

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Lichenoid dermatitis [title]

Cite this page: Lichenoid dermatitis. PathologyOutlines.com website. http://pathologyoutlines.com/topic/skinnontumorlichenoiddermatitis.html. Accessed December 7th, 2016.
Definition / General
  • A histological pattern, not a distinct clinical entity
  • Due to drug eruption, actinic keratosis, lupus erythematosus, acute graft versus host disease, regressing melanoma and dermatofibroma
  • May be a delayed hypersensitivity reaction
  • May present as a neoplasm
Micro Description
  • Dense, bandlike lymphocytic infiltrate in dermis that obscures dermoepidermal junction
  • Cytoplasmic vacuolization of basal keratinocytes with a brightly eosinophilic cytoplasm; the nucleus becomes extruded to become round/oval eosinophilic bodies (colloid bodies)
  • Regenerated epithelium has a disorderly basement membrane
  • May have large cell acanthoma or solar lentigo within the lesion