Skin-nontumor / Clinical dermatology
Other dermatoses
Gyrate erythema

Author: Mowafak Hamodat, M.D., MB.CH.B, MSc., FRCPC (see Authors page)

Revised: 28 June 2016, last major update July 2011

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PubMed Search: Gyrate erythema

Cite this page: Gyrate erythema. PathologyOutlines.com website. http://pathologyoutlines.com/topic/skinnontumorgyrateerythema.html. Accessed December 9th, 2016.
Definition / General
  • Various erytematous eruptions with a curvilinear ("gyrate") appearance:
  • Erythema annulare centrifugum: most common gyrate erythema, but etiology unknown; may grow over weeks, resolves in 1 - 2 months
  • Erythema marginatum rheumaticum: due to rheumatic fever, now extremely rare
  • Erythema gyratum repens: uncommon, paraneoplastic process associated with internal malignancy (eMedicine)
  • Erythema chronicum migrans: occurs after a tick bite, may be associated with Lyme disease (Wikipedia)
Terminology
  • Also called figurate erythema
Case Reports
  • 64 year old woman with pruritic, erythematous plaques on abdomen and back that appeared and disappeared (Case of Week #71)
Clinical Features
  • Multiple waves of curvilinear erythema and scale
  • Rash may migrate and be pruritic
Clinical Images

Images hosted on other servers:

Erythema annulare centrifugum - Pregnant woman

Erythema gyratum repens

Erythema marginatum rheumaticum

Erythema chronicum migrans

Micro Description
  • Non-specific changes
  • Dense perivascular lymphocytic infiltrate of superficial dermis and possibly deep reticular dermis
  • Lymphocytes are well demarcated and adjacent to vessels ("coat sleeve" or "pipe stem" appearance in erythem annulare centrifugum)
  • Variable epidermal spongiosis, mild ancanthosis and parakeratosis; may have focal vacuolar changes
Micro Images

Images hosted on PathOut servers:

Erythema gyrated repent (Case of the Week #71)


Images hosted on other servers:

Erythema annulare centrifugum - Pregnant woman

Erythema chronicum migrans

Positive Stains
  • Erythema gyratum repens: occasional presence of C3, C4 and IgG at the basement membrane zone with direct immunofluorescence