Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Advertisement

Skin-nontumor / Clinical Dermatology

Other dermatoses

Erythema elevatum diutinum


Reviewer: Nat Pernick, M.D., PathologyOutlines.com, Inc. (see Reviewers page)
Revised: 29 July 2011, last major update July 2011
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.

General
=========================================================================

● Bilaterally symmetric erythematous or violaceous plaques or nodules, often over outer surface of joints
● Systemically ill patients or associated with HIV
● May be related to granuloma faciale
● May be an immune-complex vasculitis induced by chronic antigen exposure

Case reports
=========================================================================

● 53 year old man with HIV (Dermatol Online J 2003;9:37)

Clinical images
=========================================================================


   
Numerous firm brown tumors on extensor surfaces of extremities

Gross images
=========================================================================



Nodules removed from hand

Micro description
=========================================================================

● Leukocytoclastic vasculitis, progressing to fibrosis and onion skinning around vessels
● Extracellular lipid deposits may be present in late lesions; no/rare eosinophils

Micro images
=========================================================================


   
Small vessel vasculitis


Whorled fibromatous pattern


Bland spindle cells, neutrophils and extravasated red blood cells

Differential diagnosis
=========================================================================

Localized chronic fibrosing vasculitis: different clinical findings

Additional references
=========================================================================

eMedicine

End of Skin-nontumor / Clinical Dermatology > Other dermatoses > Erythema elevatum diutinum


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).