Table of ContentsClinical features | Diagnosis | Case reports | Clinical images | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosis
Cite this page: Behcet's disease. PathologyOutlines.com website. http://pathologyoutlines.com/topic/skinnontumorbehcetdisease.html. Accessed July 27th, 2017.
- Chronic condition with canker sores or ulcers in mouth and genitals and inflammation in parts of eye (National Institutes of Health)
- May also cause arthritis, skin problems, inflammation of digestive tract and CNS
- Most common along “Old Silk Route” from Japan and China to Mediterranean; rare in U.S.
- Some skin lesions resemble acne but occur throughout body; also erythema nodosum with ulceration
- Aphthous ulcers in mouth (lips, tongue, inside cheek) of almost all patients; are numerous, frequent, large and painful
- May be fatal due to ruptured aneurysms or severe neurological complications
- 34 year old man with aphthous stomatitis, then painful erythematous nodules on lower extremities (Dermatol Online J 2010;16:18)
Microscopic (histologic) description
- Leukocytoclastic vasculitis and panniculitis
- Also superficial and deep perivascular infiltrates of lymphocytes and neutrophils
- Some vessels contain thrombi
- Also suppurative folliculitis, intraepidermal or subepidermal vesicles
Microscopic (histologic) images
- Localized chronic fibrosing vasculitis: different clinical findings